PUBLICATIONS
Publications
2024
[127] Z. Yao, K. Zhu, T. Gu, O. J. Schmitz, D. Li, An active derivatization detection method for inline monitoring the isolation of carbohydrates by preparative liquid chromatography, Journal of Chromatography A (2024) doi.org/10.1016/j.chroma.2024.464730
[126] A. K. Mallik, L. Montero, S. W. Meckelmann O. J. Schmitz, Facile preparation of embedded polar group-containing pentafluorophenyl stationary phases for highly selective separations of diverse analytes, Journal of Chromatography A (2024) 1717:464688
[125] M. Rogava, T. J. Aprati, W.-Y. Chi, J. C. Melms, C. Hug, S.H. Davis, E.M. Earlie, C. Chung, S. K. Deshmukh, S. Wu, G. Sledge, S. Tang, P. Ho, A. D. Amin, L. Caprio, C. Gurjao, S. Tagore, B. Ngo, M. J. Lee, G. Zanetti, Y. Wang, S. Chen, W. Ge, L. Martins Nascentes Melo, G. Akkies, J. Rösler, G. T. Gibney, O. J. Schmitz, M. Sykes, R. J. Creusot, T. Tüting, D. Schadendorf, M. Röcken, T. K. Eigentler, A. Molotkov, A. Mintz, S. F. Bakhoum, S. Beyaz, L. C. Cantley, P. K. Sorger, S. W. Meckelmann, A. Tasdogan, D. Liu, A. M. Laughney, B. Izar, Loss of Pip4k2c confers liver-metastatic organotropism, Nature Cancer (2024) doi.org/10.1038/s43018-023-00704-x
[124] A. Pape, O. J. Schmitz, Dielectric barrier discharge in mass spectrometry - an overview over plasma investigations and ion sources applications, Trends in Analytical Chemistry (2024) 170:117420
2023
[123] S. Imada, H. Shin, S. Khawaled, S. W. Meckelmann, C. A Whittaker, R. Oliveira Corrêa, D. Pradhan, G. Calibasi-Kocal, L. Martins Nascentes Melo, G. Allies, P. Wittenhofer, O. J. Schmitz, J. Roper, M. Aurelio Ramirez Vinolo, C.-W. Cheng, A. Tasdogan, Ö. H Yilmaz, Post-fast refeeding enhances intestinal stem cell-mediated regeneration and tumourigenesis through mTORC1-dependent polyamine synthesis, Res Sq [Preprint]. 2023 Jan 10:rs.3.rs-2320717. doi: 10.21203/rs.3.rs-2320717/v1. PMID: 36711807; PMCID: PMC9882602.
[122] M. M. A. Omar, A. A. Elbashir, O. J. Schmitz, A. K. Ziyada, A. Osman, Validation of high-performance liquid chromatography coupled with LTQ orbitrap mass spectrometry for analysis of acrylamide, Journal of Food Measurement and Characterization, doi.org/10.1007/s11694-023-02223-w
[121] A. Mallik, L. Montero, J. Roesler, S. Meckelmann, O. J. Schmitz, Surface-modification of silica with beta-alanine derivative for unique applications in liquid chromatography, ACS Applied Materials & Interfaces (2023) 15(46):54176-54184, doi.org/10.1021/acsami.3c11932
[120] L. Mondello, P. Dugo, P. Donato, M. Herrero, L. Montero, Oliver J. Schmitz, Comprehensive two-dimensional liquid chromatography, Nature Reviews Methods Primers (2023) 3:86, doi.org/10.1038/s43586-023-00269-0
[119] J. F. Ayala-Cabrera, L. Montero, T. Sahlabji, O. J. Schmitz, Comprehensive two-dimensional gas chromatography with flow modulator coupled via tube plasma ionization to an atmospheric pressure high-resolution mass spectrometer for the analysis of vermouth volatile profile, Analytical and Bioanalytical Chemistry (2023) 415(13):2561-2573, doi.org/10.1007/s00216-023-04688-6
[118] A. K. Mallik, L. Montero, S. W. Meckelmann, O. J. Schmitz, Design of -Alanine-Derived Novel C18 Stationary Phase Containing Embedded Urea and Amide Groups for the Separation of Versatile Analytes, Analytical Chemistry (2023) 95:6172–6181
[117] J. Lu, X. Hiong, M. Ma, B. Chen, Y. Chen, O. J. Schmitz, Enhancing the compatibility of normal-phase chromatography x reversed−phase chromatography by combination of low−temperature sensitive aqueous-phase compatible normal- phase chromatography and at−column dilution modulation, Journal of Chromatography A (2023) 1691:463821
[116] L. Montero, J. F. Ayala-Cabrera, F. F. Bristy, O. J. Schmitz, Multi-2D LC × LC as a Novel and Powerful Implement for the Maximum Separation of Complex Samples, Analytical Chemistry (2023) 95:3398-3405
[115] J. F. Ayala-Cabrera, L. Montero, S. W. Meckelmann, F. Uteschil, O. J. Schmitz, Review on atmospheric pressure ionization sources for gas chromatography-mass spectrometry. Part I: Current ion source developments and improvements in ionization strategies, Analytica Chimica Acta (2023) 1238:340353
[114] J. F. Ayala-Cabrera, L. Montero, S. W. Meckelmann, F. Uteschil, O. J. Schmitz, Review on atmospheric pressure ionization sources for gas chromatography-mass spectrometry. Part II: Current applications, Analytica Chimica Acta (2023) 1238:340379
2022
[113] J. F. Ayala-Cabrera, L. Montero, S. W. Meckelmann, F. Uteschil, O. J. Schmitz, Review on atmospheric pressure ionization sources for gas chromatography-mass spectrometry. Part I: Current ion source developments and improvements in ionization strategies., Analytica Chimica Acta (2022) https://doi.org/10.1016/j.aca.2022.340353
[112] L. Kuschmierz, M. Meyer, C. Bräsen, J. Wingender, O. J. Schmitz, B. Siebers, Exopolysaccharide composition and size in Sulfolobus acidocaldarius biofilms, accepted in Frontiers Microbiology
[111] V. Dosedělová, M. Laštovičková, J. F. Ayala-Cabrera, J. Dolina, Š. Konečný , O. J. Schmitz, P. Kubáň, Quantification and identification of bile acids in saliva by liquid chromatography-mass spectrometry: Possible non-invasive diagnostics of Barret's esophagus?, accepted in Journal of Chromatography A
[110] S. K. Heuser, A. LoBue, J. Li, Z. Zhuge, F. Leo, T. Suvorava, A. Olson, R. Schneckmann, D. D. Guimaraes Braga, T. Srivrastava, L. Montero, O. J. Schmitz, J. P. Schmitt, M. Grandoch, E. Weitzberg, J. O. Lundberg, J. Pernow, M. Kelm, M. Carlström, M. M. Cortese-Krott, Downregulation of eNOS and preserved endothelial function in endothelial-specific arginase 1-deficient mice, accepted in Nitric Oxide
[109] Y. Großmann, U. Schreiber, C. Mayer, O. J. Schmitz, Aliphatic aldehydes in the Earth’s crust – remains of prebiotic chemistry? Life (2022) 12: 925; https://doi.org/10.3390/life12070925
[108] J. F. Ayala-Cabrera, J. Turkowski, F. Uteschil, O. J. Schmitz, Development of a tube plasma ion source for gas chromatography-mass spectrometry analysis and comparison with other atmospheric pressure ionization techniques, accepted in Analytical Chemistry
[107] T. Koehler, J. Wingender, M. Lueling, S. W. Meckelmann, U. Telgheder, O. J. Schmitz, Characterization of the extracellular volatile metabolome of Pseudomonas aeruginosa applying an in vitro biofilm model under cystic fibrosis-like conditions, Frontiers in Bioscience – Landmark (2022), 27:156
[106] A. R. Ziefuß, T. Hupfeld, S. W. Meckelmann, M. Meyer, O. J. Schmitz, W. Kaziur-Cegla, L. K. Tintrop, T. Schmidt, B. Gökce, S. Barcikowski, Ultrafast cold-brewing of coffee by picosecond-pulsed laser extraction, npj Science of Food (2022) 16:19; 10.1038/s41538-022-00134-6
[105] L. Montero, S. Meckelmann, H. Kim, J. F. Ayala-Cabrera, O. J. Schmitz, Differentiation of the cannabinoid and phenolic compounds of industrial hemp varieties by LC×LC-HRMS, Analytical and Bioanalytical Chemistry (2022); https://doi.org/10.1007/s00216-022-03925-8
2021
[104] M. Meyer, L. Montero, S. W. Meckelmann, O. J. Schmitz, Comparative study for analysis of carbohydrates in biological samples, Analytical and Bioanalytical Chemistry (2021), doi.org/10.1007/s00216-021-03845-z
[103] K. Tötsch, J. Fjeldsted, S. Stow, O. J. Schmitz, S. Meckelmann, Effect of Sampling Rate and Data Pretreatment for targeted and non-targeted Analysis by means of Liquid Chromatography coupled to Drift Time Ion Mobility Quadruple Time-Of-Flight Mass Spectrometry, accepted in Journal of the American Society for Mass Spectrometry
[102] T. T. Bui, T. H. Nguyen, H. A. Duong, H. V. Pham, O. J. Schmitz, V. T. Nguyen, Q. A. Ngo, Hepatoprotective effect of water extract formulation from Stixis suaveolens and Pandanus tonkinensis against liver injury induced by acetaminophen and in vitro CCl4-induced toxicity, accepted in Vietnam Journal of Chemistry
[101] D. Brecht, F. Uteschil, O. J. Schmitz, Development of an inverse-low-temperature plasma ionization source for LC-MS, Rapid Communication in Mass Spectrometry (2021) 34:e8845
[100] F. E. O. Suliman, S. K. Al Burtomani, A. A. Elbashir, O. J. Schmitz, Capillary electrophoresis and molecular modeling of the chiral separation of aromatic amino acids using α/β‐cyclodextrin and 18‐crown‐6, accepted in Electrophoresis
[99] J. F. Ayala-Cabrera, C. Lipok, J. Li, E. Moyano, O. J. Schmitz, F. J. Santos, Ionic Liquid Stationary Phase for Improving Comprehensive Two-dimensional Gas Chromatographic Separation of Polychlorinated Naphthalenes, Journal of Chromatography A (2021) 1635: 461732-461737
[98] J. F. Ayala-Cabrera, C. Lipok, E. Moyano, O. J. Schmitz, F. J. Santos, Atmospheric Pressure Ionization for Gas Chromatography-High Resolution Mass Spectrometry Determination of Polychlorinated Naphthalenes,
Chemosphere (2021) 263:127963-127973
[97] P. Rusch, A. V. Hirner, O. Schmitz, R. Kimmig, O. Hoffmann, M. Diel, Zinc distribution within breast cancer tissue of different intrinsic subtypes, Archives of Gynecology and Obstetrics (2021) 303:195–205(2021)
2020
2020
[96] L. Montero, O.J. Schmitz, S.W. Meckelmann, Chemical Characterization of eight Herbal Liqueurs by means of Liquid Chromatography Coupled with Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry, Journal of Chromatography A (2020) 1631:461560-461571
[95] C. Lipok, F. Uteschil, O. J. Schmitz*, Development of an atmospheric pressure chemical ionization interface for GC-MS, Molecules (2020) 25:3253-3265
[94] J. Li, C. Rumancev, H. V. Lutze, T. C. Schmidt, A. Rosenhahn, O. J. Schmitz*, Effect of ozone stress on the intracellular metabolites from Cobetia marina, Analytical and Bioanalytical Chemistry (2020) 412:5853-5861
[93] S. Hellhake, S. W. Meckelmann, M. T. Empl, K. Rentmeister, W. Wißdorf, P. Steinberg, O. J. Schmitz, T. Benter, N. H. Schebb, Non-targeted and targeted analysis of oxylipins in combination with charge switch derivatization by ion mobility high resolution mass spectrometry, Analytical and Bioanalytical Chemistry (2020) 412:5743-5757
[92] D. Brecht, F. Uteschil, O. J. Schmitz* Development of a fast-switching dual (ESI/APCI) ionization source for liquid chromatography mass spectrometry, Rapid Communication in Mass Spectrometry (2020) 34 (17):e8845
[91] B. Peng, D. Kopczynski, B. Pratt, C. Ejsing, B. Burla, M. Hermansson, P. Benke, S. Tan, M. Chan, F. Torta, D. Schwudke, S. Meckelmann, C. Coman, O. J. Schmitz, B. MacLean, M.-C. Manke, O. Borst, M. Wenk, N. Hoffmann R. Ahrends LipidCreator workbench to probe the lipidomic landscape, Nature Communications (2020) 11:2057-2070
[90] T. Koehler, I. Ackermann, D. Brecht, F. Uteschil, J. Wingender, U. Telgheder, O. J. Schmitz* Analysis of volatile metabolites from in vitro biofilms of Pseudomonas aeruginosa with thin-film microextraction by thermal desorption gas chromatography-mass spectrometry, Analytical and Bioanalytical Chemistry (2020) 412:2881–2892
[89] Y. Chen, L. Montero, J. Luo, J. Li, O. J. Schmitz* Application of the new at-column dilution (ACD) modulator for the two-dimensional RPxHILIC analysis of Buddleja davidii, Analytical and Bioanalytical Chemistry (2020) 412:1483–1495 (open access)
[88] Q. A. Ngo, D. T. Hoang, T. Duc, H. A. Duong, O. J. Schmitz, H. V. Pham Characterization of volatile components from Ethyl acetate extract of Stixis suaveolens (Roxb.) by comprehensive two-dimensional gas chromatography hyphenated with a time-of-flight mass spectrometer, Vietnam Journal of Chemistry (2020) 58:261-266
2019
[87] Y. Chen, L. Montero, O. J. Schmitz* Advance in on-line two-dimensional liquid chromatography modulation technology, Trends in Analytical Chemistry (2019) 120:115647
[86] Y. Chen, J. Li, O. J. Schmitz*, Development of an at-column dilution modulator for flexible and precise control of dilution factors to overcome mobile phase incompatibility in comprehensive two-dimensional liquid chromatography, Analytical Chemistry (2019)
91:10251-10257
[85] A. Doell, O. J. Schmitz, M. Hollmann, Shedding light into the subcutis – A mass spec based immuno-capture assay enables full characterization of therapeutic antibodies after injection in-vivo, Analytical Chemistry (2019) 91: 9490-9499
[84] C. Hellmann, O. J. Schmitz*, How to deal with mercury in sediments ? A critical review about used methods for the speciation of mercury in sediments, Chromatographia (2019) 82: 125-141
[83] D. Brecht, F. Uteschil, O. J. Schmitz*, Thermogravimetry coupled to an atmospheric pressure photo ionization quadrupole mass spectrometry for the product control of pharmaceutical formulations and the analysis of plasticizers in polymers, accepted in Talanta
[82] C. Koch, M. Nachev, J. Klein, D. Koester, O. J. Schmitz, T. Schmidt, B. Sures, Degradation of the polymeric brominated flame retardant “Polymeric FR” by heat and UV, accepted in Environmental Science & Technology
2018
[81] S. Brüggen, O. J. Schmitz*, A new concept for regulatory water monitoring via high-performance liquid chromatography coupled to high-resolution mass spectrometry, accepted in Journal of Analysis and Testing
[80] K. Jooß, S. W. Meckelmann, J. Klein, O. J. Schmitz, C. Neusüß, Capillary zone electrophoresis coupled to drift tube ion mobility-mass spectrometry for the analysis of native and APTS-labeled N-glycans, accepted in Analytical and Bioanalytical Chemistry as Paper in Forefront
[79] L. C. Weiss, B. Albada, S. M. Becker, S. W. Meckelmann, J. Klein, M. Meyer, O. J. Schmitz, U. Sommer, M. Leo, J. Zagermann, N. Metzler-Nolte, R. Tollrian, The scent of predation: Identification of an aquatic infochemical – the Chaoborus kairomone, Nature Chemical Biology (2018) 14:1133-1139
[78] V. Hinnekamp, J. Klein, S. Meckelmann, P. Balsaa, T. Schmidt, O. J. Schmitz*, Comparison of CCS Values Determined by Traveling Wave Ion Mobility Mass Spectrometry and Drift Tube Ion Mobility Mass Spectrometry, Analytical Chemistry (2018) 90:12042-12050
[77] C. Mayer, U. Schreiber, M. J. Dávila, O. J. Schmitz, A. Bronja, M. Meyer, J. Klein, S. W. Meckelmann Molecular Evolution in a Peptide-Vesicle System, Life (2018) 8: 16 (open access)
[76] C. Lipok, J. Hippler, O. J. Schmitz* A four dimensional separation method based on continuous heart-cutting gas chromatography with ion mobility and high resolution mass spectrometry, Journal of Chromatography A (2018) 1536:50-57
2017
[75] S. Horst, O. J. Schmitz*, Quantitative analysis of bisphenol A in recycled paper with a novel Direct Inlet Probe – Atmospheric Pressure Photoionization-IonTrap-MS, Journal of Analysis and Testing (2017) 1:255-263 (open access)
[74] A. A. Deeb, S. Stephan, O. J. Schmitz, T. C. Schmidt Suspect screening of micropollutants and their transformation products in advanced wastewater treatment, Science of the Total Environment (2017) 601-602:1247-1253
[73] P. Weyrauch, A. V. Zaytsev, S. Stephan, L. Kocks, O. J. Schmitz, B. T. Golding, R. U. Meckenstock, Conversion of cis-2-carboxycyclohexylacetyl-CoA in the downstream pathway of anaerobic naphthalene degradation, Environmental Microbiology (2017) 19:2819-2830
[72] U. Schreiber, C. Mayer, O. J. Schmitz, P. Rosendahl, A. Bronja, M. Greule, F. Keppler, I. Mulder, T. Sattler, H. F. Schöler Organic compounds in fluid inclusions of Archean quartz – archives of prebiotic chemistry on early Earth, PLoS ONE 12(6): e0177570
[71] H. Y. Aboul-Enein, A. A. Elbashir, O. J. Schmitz, Application of capillary electrophoresis with capacitively coupled contactless conductivity detection (CE-C4D): an update, Biomedical Chromatography (2017) e3945 (DOI 10.1002/bmc.3945)
[70] S. Stephan, J. Hippler, T. Köhler, D. Brecht, O. J. Schmitz*, A powerful four-dimensional separation method for complex samples, Journal of Analysis and Testing (2017) 1:1-9 (open access)
[69] A. Abu awwad, T. Arafat, O. J. Schmitz*, Study the Influence of Licorice and Pomegranate Drinks on Nicotine Metabolism in Human Urine, Journal of Pharmaceutical and Biomedical Analysis 132 (2017) 60-65
[68] M. M. A. Omar, A. A. Elbashir , O. J. Schmitz*, Capillary Electrophoresis Method with UV-detection for Analysis of Free Amino Acids concentrations in Food, Food Chemistry (2017) 214:300-307
2016
[67] A. Abu awwad, T. Arafat, O. J. Schmitz*, Determination of Nicotine and Cotinine in Human Blood by Dried Blood Spot-LC-Orbitrap MS Technique, Journal of Analytical & Pharmaceutical Research (2016) 3:1-7
[66] C. Koch, A. Dundua, J. Aragon-Gomez, M. Nachev, S. Stephan, S. Willach, M. Ulbricht, O.J. Schmitz, T. Schmidt, B. Sures Degradation of polymeric brominated flame retardants: Development of an analytical approach using PolyFR and UV irradiation, Environmental Science & Technology (2016) 50:12912–12920
[65] S. Scherer, E. Wollrab, L. Codutti, T. Carlomagno, S. Gomes da Costa, A. Volkmer, A. Bronja, O. J. Schmitz, A. Ott, Chemical analysis of a "Miller-type" complex prebiotic broth Part II: gas, oil, water and the oil/water-interface, Origins of Life and Evolution of Biospheres, DOI 10.1007/s11084-016-9528-8
[64] S. Stephan, J. Hippler, T. Köhler, A. Deep, T. Schmidt, O. J. Schmitz*, Contaminant screening of wastewater with HPLC-IM-qTOF-MS and LC+LCIM-qTOF-MS using a CCS database, Analytical and Bioanalytical Chemistry (2016) 408:6545-6555
[63] A. Abu awwad, T. Arafat, O. J. Schmitz*, Simultaneous determination of nicotine, cotinine and nicotine N-oxide in human plasma, semen and sperm by LC-Orbitrap MS, Analytical and Bioanalytical Chemistry (2016) 408:6473-6481
[62] T. Arafat, B. Arafat, A. Abu awwad, O. J. Schmitz, Determination of Fenofibric Acid in Human Plasma by LC-MS/MS and LC-UV, Chromatography (2016) 79:685-692
[61] C. Lenzen, G. A. Winterfeld, O. J. Schmitz*, Comparison of Piracetam measured with HPLC-DAD, HPLC-ESI-MS, DIP-APCI-MS and a newly developed and optimized DIP-ESI-MS, Analytical and Bioanalytical Chemistry (2016) 408:4103-4110
[60] S. Stephan, C. Jakob, J. Hippler, O. J. Schmitz*, A novel four-dimensional analytical approach for complex samples, Analytical and Bioanalytical Chemistry (2016) 408:3751-3759
[59] P. Rosendahl, J. Hippler, O. J. Schmitz*, O. Hoffmann, P. Rusch, Cyclic volatile methylsiloxanes in human blood as markers for ruptured silicone gel-filled breast implants, Analytical and Bioanalytical Chemistry (2016) 408:3309-3317
[58] A. Li, O. J. Schmitz, S. Stephan, C. Lenzen, P. Y.-K. Yue, K. Li, H. Li, K. S.-Y. Leung, Photocatalytic transformation of acesulfame: transformation products identification and embryotoxicity study, Water Research (2016) 89:68-75
[57] D. Klink, O. J. Schmitz*, SFC-APLI-(TOF)MS – a novel hyphenation of Supercritical Fluid Chromatography to Atmospheric Pressure Laser Ionization Mass Spectrometry, Analytical Chemistry (2016) 88:1058-1064
2015
[56] D. Li, L. Gan, A. Bronja; O. J. Schmitz*, Gas chromatography coupled to atmospheric pressure ionization mass spectrometer (GC-API-MS): Review, Analytica Chimica Acta (2015) 891:43-61
[55] F. O. Suliman, A. A. Elbashir, O. J. Schmitz, Study on the separation of ofloxacin enantiomers by hydroxyl-propyl-ß-cyclodextrin as a chiral selector in capillary electrophoresis: a computational approach, Journal of Inclusion Phenomena and Macrocyclic Chemistry (2015) DOI 10.1007/s10847-015-0547-2
[54] E. Deibel, D. Klink, O. J. Schmitz*, New derivatization strategies for the ultrasensitive analysis of non-aromatic analytes with APLI-TOF-MS, Analytical and Bioanalytical Chemistry (2015) 407:7425-7434
[53] M. M. A. Omar, A. A. Elbashir, O. J. Schmitz*, Determination of acrylamide in Sudanese food by high performance liquid chromatography coupled with LTQ Orbitrap mass spectrometry, Food Chemistry (2015) 176:342-349
[52] D. Li, C. Jakob, O. J. Schmitz*, Review: Practical considerations in comprehensive two-dimensional liquid chromatography systems (LCxLC) with Reversed-phases in both dimensions, Analytical and Bioanalytical Chemistry (2015) 407:153-167
[51] V. Elsner, V. Wulf, M. Wirtz, O. J. Schmitz*, Reproducibility of retention time and peak area in comprehensive two-dimensional liquid chromatography, Analytical and Bioanalytical Chemistry (2015) 407:279-284
[50] D. Li, O. J. Schmitz*, Comprehensive two-dimensional liquid cromatography tandem DAD and accurate mass QTOF-MS for the analysis of flavinoids and iridoid glycosides in Heditys diffusa, Analytical and Bioanalytical Chemistry (2015) 407:231-240
2014
[49] A. A. Elbashir, S. Krieger, O. J. Schmitz*, Simultaneous Determination of Polyamines and Acetylpolyamines in human urine by Capillary Electrophoresis with Fluorescence Detection, Electrophoresis 35 (2014) 570-576
[48] D. Li, R. Dück, O. J. Schmitz*, The Advantage of Mixed-Mode Separation in the First Dimension of Comprehensive Two-Dimensional Liquid-Chromatography, J. Chromatogr. A (2014) 1358:128-135
[47] S. Krieger, O. J. Schmitz*, Non-destructive mass spectrometric plasticiser screening using a direct inlet probe-atmospheric pressure chemical ionization source and ion trap MS, Rapid Commun. Mass Spectrom. 28 (2014) 1862-187
[46] A. A. Elbashir, M. M. A. Omar, W. A. W. Ibrahim, O. J. Schmitz, H. Y. Aboul-Enein Acrylamide, Analysis in Food by Liquid Chromatographic and Gas Chromatographic Methods, Critical Reviews in Analytical Chemistry, 44 (2014) 107-141
2013
[45] S. Krieger, H. Hayen, O. J. Schmitz*, Quantification of coumarin in cinnamon and woodruff-beverages using DIP-APCI-MS and LC-MS, Analytical and Bioanalytical Chemistry DOI: 10.1007/s00216-013-7238-x
[44] S. Pelz, J.-M. Zhang, I. Kanelidis, D. Klink, L. Hyzak, V. Wulf, O. J. Schmitz, J.-C. Gasse, R. Frahm, A. Pütz, A. Colsmann, U. Lemmer, E. Holder, Synthesis and Characterization of Star-Shaped Donor–Acceptor–Donor Structures, Eur. J. Org. Chem. 2013, 4761-4769
[43] D. Li, O. J. Schmitz*, Using of shift gradient in second dimension to improve the separation space in comprehensive two-dimensional liquid chromatography, Analytical and Bioanalytical Chemistry 405 (2013) 6511-6517
[42] N. Wienand, M. Constapel, K. Budde, J. Marzinkowski, S. Gäb, O. J. Schmitz*, Degradation of a Fluorine-Free Perfluorooctane Sulfonate Substitute in Chromium Plating Solutions, Chem. Eng. Technol. 36 (2013) 390-397
[41] L. Hyzak, S. Giese, H.-W. Kling, V. Wulf, D. Melchior, M. Köhler, O. J. Schmitz*, Improvements to the compressed-sample (CS) technique for MALDI-TOF mass spectrometry, Analytical and Bioanalytical Chemistry 405 (2013) 1417-1424
[40] S. Krieger, A. von Trotha, K. S.-Y. Leung, O. J. Schmitz*, Development, optimization and use of an APCI source with temperature-controlled vaporization of solid and liquid samples, Analytical and Bioanalytical Chemistry 405 (2013) 1373-1381
2012
[39] V. Elsner, S. Laun, D. Melchior, M. Köhler, O. J. Schmitz*, Analysis of fatty alcohol derivatives with comprehensive two-dimensional liquid chromatography coupled with mass spectrometry, Journal of Chromatography A 1268 (2012) 22-28
[38] G. Dierkes, S. Krieger, R. Dück, A. Bongartz, O. J. Schmitz, H. Hayen, HPLC-MS Profiling of Phenolic Compounds for Evaluation of Olive Oil Bitterness and Pungency, J. Agric. Food Chem. 60 (2012) 7597-7606
[37] R. Dück, H. Sonderfeld, O. J. Schmitz*, A simple method for the determination of peak distribution in comprehensive two-dimensional liquid chromatography, J. Chromatogr. A 1246 (2012) 69-75
2011
[36] L. Hyzak, R. Moos, F. von Rath, V. Wulf, M. Wirtz, D. Melchior, H.-W. Kling, M. Köhler, S. Gäb, O. J. Schmitz*, Quantitative MALDI-(TOF)MS analysis of synthetic polymers and peptides, Analytical Chemistry 83 (2011) 9467-9471
2010
[35] N. Tian, D. Lenkeit, S. Pelz, L. H. Fischer, D. Escudero, R. Schiewek, D. Klink, O. J. Schmitz, L. González, M. Schäferling, E. Holder, Structure-property relationship of red and green emitting iridium(III) complexes with respect to their temperature and oxygen sensitivity, European Journal of Inorganic Chemistry (2010), 4875-4885
[34] V. Wulf, N. Wienand, M. Wirtz, H.-W. Kling, S. Gäb, O. J. Schmitz*, Analysis of special surfactants by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry, Journal of Chromatography A 1217 (2010) 749-754
[33] R. Dück, V. Wulf, M. Geißler, H.-U. Baier, M. Wirtz, H.-W. Kling, S. Gäb, O. J. Schmitz*, Combination of chemical and electron-impact ionisation with GCxGC-qMS for the characterization of fatty alcohol alkoxylate polymers in the low molecular range up to 700 Da, Analytical and Bioanalytical Chemistry 396 (2010) 2273-2283
[32] B. de Montera, D. El-Zeihery, S. Müller, H. Jammes, G. Brem, H.-D. Reichenbach, F. Scheipl, P. Chavatte-Palmer, V. Zakhartchenko, O. J. Schmitz, E. Wolf, J.-P. Renard, S. Hiendleder, Quantification of leukocyte genomic 5-methylcytosine levels reveals epigentic plasticity of healthy adult cloned cattle, Cellular Reprogramming 12 (2010) 175-181
2009
[31] N. Tian, A. Thiessen, R. Schiewek, O. J. Schmitz, D. Hertel, K. Meerholz, E. Holder, Efficient Synthesis of Carbazolyl- and Thienyl-Substituted β-Diketonates and Properties of Their Red and Green Light-Emitting Ir(III) Complexes, Journal of Organic Chemistry 74 (2009) 2718-2725
[30] C. Fu, G. Lu, O. J. Schmitz, Z. Li, K. S.-Y. Leung, Improved Chromatographic Fingerprints for Facile Differentiation of Two Ganoderma Spp., Biomedical Chromatography 23 (2009) 280-288
2008
[29] R. Schiewek, R. Mönnikes, V. Wulf, S. Gäb, K. J. Brockmann, T. Benter, O. J. Schmitz*, A universal ionization label for the APLI-(TOF)MS analysis of small molecules and polymers, Angewandte Chemie Int. Ed. 47 (2008) 9989-9992 und Angewandte Chemie 120 (2008) 10138-10142
[28] W. Chan, H. Yue, W. T. Poon, Y.-W. Chan, O. J. Schmitz, D. W. J. Kwong, R. N. S. Wong, Z. Cai, Quantification of aristolochic acid-derived DNA adducts in rat kidney, liver by using liquid chromatography-electrospray ionization mass spectrometry, Mutation Research 646 (2008) 17-24
[27] R. Schiewek, M. Lorenz, K. J. Brockmann, T. Benter, S. Gäb, O. J. Schmitz*, Development of a multimode ion-source for LC- and GC-MS, Analytical and Bioanalytical Chemistry 392 (2008) 87-96
[26] P. Schmitt-Kopplin, M. Englmann, R. Rossello-Mora, R. Schiewek, K. J. Brockmann, T. Benter, O. J. Schmitz*, Combining Chip-ESI with APLI (cESILI) as a multimode source for the analysis of complex mixtures with ultrahigh resolution mass spectrometry, Analytical and Bioanalytical Chemistry 391 (2008) 2803-280
[25] V. M. Arlt, M. Stiborová, C. J. Henderson, M. Thiemann, E. Frei, D. Aimová, R. Singh, G. Gamboa da Costa, O. J. Schmitz, P. B. Farmer, C. R. Wolf, D. H. Phillips, Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with Hepatic Cytochrome P450 Reductase Null mice, Carcinogenesis 29 (2008) 656-665
[24] M. Lorenz, R. Schiewek, K. J. Brockmann, O. J. Schmitz, S. Gäb, T. Benter, The destribution of ion acceptance in atmospheric pressure ion sources: Spatially resolvedAPLI measurements, Journal of the American Society for Mass Spectrometry 19 (2008) 400-410
[23] G. Vogt, M. Huber, M. Thiemann, G. van den Boogaart, O. J. Schmitz, C. D. Schubart, Production of different phenotypes from the same genotype in the same environment by developmental variation, Journal of Experimental Biology 211 (2008) 510-523
2007
[22] R. Schiewek, M. Schellenträger, R. Mönnikes, M. Lorenz, R. Giese, K. J. Brockmann, S. Gäb, T. Benter, O. J. Schmitz*, Ultra-sensitive determination of polycyclic aromatic compounds with atmospheric-pressure laser ionization as an interface for GC-MS, Analytical Chemistry 79 (2007) 4135-4140
[21] J. Hübner, R. Taheri, D. Melchior, H.-W. Kling, S. Gäb, O. J. Schmitz*, Analysis of tensides in complex samples with comprehensive two-dimensional gas chromatography coupled with a time-of-flight mass spectrometer, Analytical and Bioanalytical Chemistry 388 (2007) 1755-1762
[20] R. Schiewek, M. Wirtz, M. Thiemann, K. Plitt, G. Vogt, O. J. Schmitz*, Determination of the DNA methylation level of the marbled crayfish: An increase in sample throughput by an optimised sample preparation, Journal of Chromatography B 850 (2007) 548-552
2006
[19] S. Hiendleder, M. Wirtz, C. Mund, M. Klempt, H.-D. Reichenbach, M. Stojkovic, M. Weppert, H. Wenigerkind, M. Elmlinger, F. Lyko, O. J. Schmitz, E. Wolf, Tissue-specific effects of in vitro fertilization procedures on genomic cytosine methylation levels in overgrown and normal sized bovine fetuses, Biology of Reproduction 75 (2006) 17-23
[18] J. Hübner, A. Nguyen, F. Turcu, D. Melchior, H.-W. Kling, S. Gäb, O. J. Schmitz*, Analysis of alkyl polyglucosides in industrial products by capillary electrophoresis with pulsed-amperometric detection, Analytical and Bioanalytical Chemistry 384 (2006) 259-264
[17] O. J. Schmitz, Analysis of DNA modifications, Analytical and Bioanalytical Chemistry 384 (2006) 34-36
2005
[16] S. Droste, M. Schellenträger, M. Constapel, S. Gäb, M. Lorenz, K. J. Brockmann, T. Benter, D. Lubda, O. J. Schmitz*, A Silica-based Monolithic Column in capillary-HPLC and CEC coupled with ESI- MS or ES-APLI-MS, Electrophoresis 26 (2005) 4098-4103
[15] M. Corcoran, A. Parker, J. Orchard, Z. Davis, M. Wirtz, O. J. Schmitz, D. Oscier, ZAP-70 methylation status is associated with ZAP-70 expression status in chronic lymphocytic leukemia, Haematologica 90 (2005) 1078-1088
[14] M. Wirtz, C. A. Schumann, M. Schellenträger, S. Gäb, J. vom Brocke, M. L. A. Podeschwa, H.-J. Altenbach, D. Oscier, O. J. Schmitz*, CE-LIF analysis of endogenous damage in mitochondrial and genomic DNA, Electrophoresis 26 (2005) 2599-2607
[13] M. Constapel, M. Schellenträger, O. J. Schmitz, S. Gäb, K. J. Brockmann, R. Giese, T. Benter, Atmospheric-Pressure Laser Ionization: A Novel Ionization Method for Liquid Chromatography – Mass Spectrometry, Rapid Communication in Mass Spectrometry 19 (2005) 326-336
2004
[12] F. Lyko, D. Stach, A. Benner, S. Stilgenbauer, H. Döhner, M. Wirtz, M. Wießler, O. J. Schmitz*, Quantitative analysis of DNA methylation in chronic lymphocytic leukemia patients, Electrophoresis 25 (2004) 1530-1535
[11] M. Wirtz, D. Stach, H.-C. Kliem, M. Wiessler, O. J. Schmitz*, Determination of the DNA methylation level in tumor cells by capillary electrophoresis and laser-induced-fluorescence detection, Electrophoresis 25 (2004) 839-845
2003
[10] D. Stach, O. J. Schmitz, S. Stilgenbauer, A. Benner, H. Döhner, M. Wießler, F. Lyko, Capillary electrophoretic analysis of genomic DNA methylation levels, Nucleic Acids Research 31 (2003) e2
2002
[9] O. J. Schmitz, C. Wörth, D. Stach, M. Wießler, DNA adducts as biomarkers for carcinogenesis analysed by capillary electrophoresis, Angewandte Chemie Int. Ed. 41 (2002) 445-448 and Angewandte Chemie 114 (2002) 461-464
2001
[8] D. Stach, O. J. Schmitz*, Decrease in concentration of free catechins in tea over time determined by micellar electrokinetic chromatography, Journal of Chromatography A 924 (2001) 519-522
2000
[7] C. C. T. Wörth, M. Wießler, O. J. Schmitz*, Analysis of catechins and caffeine in tea extracts by micellar electrokinetic chromatography, Electrophoresis 21 (2000) 3634-3638
[6] O. J. Schmitz, E. Richter, Capillary Zone Electrophoresis with On-Line Blotting for Separation and Detection of 32P-postlabeled DNA-Adducts, Biomarkers 5(4) (2000) 314-321
[5] C. C. T. Wörth, O. J. Schmitz, M. Wießler, Synthesis of fluorescently labeled alkylated DNA-adduct standards and separation by capillary electrophoresis, Electrophoresis 21 (2000) 2086-2091
[4] K.-C. Schroff, P. Lovich, O. J. Schmitz, S. Aschhoff, E. Richter, J. Remien, Effects of cotinine at cholinergic nicotinic receptors of the sympathetic superior cervical ganglion of the mouse, Toxicology 144 (2000) 99-105
1998
[3] O. J. Schmitz, D. Melchior, W. Schuhmann, S. Gäb, Postcolumn derivatisation for selective laser-induced fluorescence detection in MEKC of fatty acid hydroperoxides, Journal of Chromatography A 814 (1998) 261-265
1997
[2] O. J. Schmitz, S. Gäb, Separation of unsaturated fatty acids and related isomeric hydroperoxides by micellar electrokinetic chromatography, Journal of Chromatography A 781 (1997) 215-221
[1] O. J. Schmitz, S. Gäb, Separation of isomeric hydroperoxides of unsaturated fatty acids by CE, Journal of Chromatography A 767 (1997) 249-253
* corresponding author
Books / Msc. Publications
2023
O. J. Schmitz, S. W. Meckelmann in Liquid Chromatography (Third Edition), Fundamentals and Instumentation, Handbookd in Separation Science, Chapter 27 – Identification and quantitation in liquid chromatography–mass spectrometry (2023) 707-726, Elsevier, https://doi.org/10.1016/B978-0-323-99968-7.00008-4
2022
S. W. Meckelmann, P. Wittenhofer, K. Tötsch, O. J. Schmitz Supercritical Fluid Chromatography coupled with Drift Tube Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry as Tool for Lipid Characterization of HepG2 Cells, LCGC (Europe) 35:207-212
2020
M. Vogel, W. Engewald, K. Dettmer‐Wilde, O. J Schmitz, M. Sperling, C. G. Huber, C. Regl, T. Berger, S. Piendl, D. Belder, F.‐Mi. Matysik
Trendbericht Analytische Chemie II: Trenntechniken und Elektroanalytik
Nachrichten aus der Chemie 68/10 (2020) 48-53
L. Mahdi, O. J. Schmitz
Metabolome Studies of Herbal Medicine Using High Performance Liquid Chromatography Ion-Mobility Mass Spectrometry
The Column 16/5 (2020) 2-7
A.-F. von Trotha, O. J. Schmitz
Qualitätskontrolle in der TCM: Chinesische Heilpflanzen auf dem Prüfstand
Springer (2020)
2019
O. J. Schmitz, Kampf der Giganten: Chromatographie gekoppelt mit Ionenmobilitäts-Massenspektrometrie oder Direkt-Injektion in ultra-hochauflösende Massenspektrometrie – Welche Plattform ist am besten für die non-target-Analyse geeignet?, chrom + food Forum März (2019) 14-15
2017
Stavros Kromidas Ed.
Das HPLC-MS-Buch für Anwender
Wiley-VCH (2017), Chapter 1
Stavros Kromidas Ed.
The HPLC-MS Handbook for Practitioners
Wiley-VCH (2017), Chapter 1
G. Schwedt, T. C. Schmidt, O. J. Schmitz, Analytische Chemie - Grundlagen, Methoden und Praxis, Wiley-VCH (2017)
2016
Stavros Kromidas Ed.
The HPLC Expert – Possibilities and Limitations of Modern HPLC
Wiley-VCH (2016), Chapter 1.1
S. Stephan, C. Jakob, J. Hippler, O. J. Schmitz, A Novel Four-Dimensional Analytical Approach For Analysis of Complex Samples, Agilent Application Note
2014
O. J. Schmitz, D. Li, Exploring Chinese Medicine with 2D-LC, The Analytical Scientist, April 2014, 42-43
Stavros Kromidas Hrsg.
Der HPLC-Experte - Möglichkeiten und Grenzen der modernen HPLC
Wiley-VCH (2014), Chapter 1.1
2013
A. von Trotha, D. Li, O. J. Schmitz, Komplexe Proben und zweidimensionale Trennmethoden, Nachrichten aus der Chemie 61 (2013) 1135-1137
S. Krieger, O. J. Schmitz, DIP-APCI – Eine neue Ionenquelle für die Produktkontrolle, Laborpraxis März (2013) 12-14
2012
H.-U. Baier, O. J. Schmitz Spectral Quality and Reproducibility in Thermal Modulation Comprehensive GCxGC–MS, The column 8(19) (2012) 9-13
2010
M. Geissler, O. J. Schmitz, M. Wirtz Characterization of fatty alcohol alkoxylate polymers with GCxGC(qmA) using chemical and electron-impact ionization, The column 6 (2010) 10-15
2008
R. Schiewek, O. J. Schmitz, Eine universelle Ionenquelle für GC- und LC-Applikationen, GIT Spezial - Separation 1 (2008) 38-39
O. J. Schmitz, T. Benter in: M. Lackner (Editor), Lasers in Chemistry:
Atmospheric pressure laser ionization
Wiley-VCH, Weinheim (2008). Chapter 22, Pages 639-654
K. J. Brockmann, T. Benter, M. Lorenz, A. L. Mangas Suárez, S. Gäb, O. J. Schmitz, R. Schiewek, R. Mönnikes in: I. Barnes, M. M. Kharytonov (Editors), Simulation and Assessment of Chemical Processes in a Multiphase Environment, Analytical innovations:
Development and applications of atmospheric pressure laser ionization (APLI)
Springer (2008), Pages 219-230
2007
O. J. Schmitz, T. Benter in: Achille Cappiello (Editor), Advances in LC–MS Instrumentation:
Atmospheric pressure laser ionization
Journal of Chromatography Library, Vol. 72 (2007), Chapter 6, Pages 89-113
2006
O. J. Schmitz, Kapillarelektrophorese – Eine unterschätzte Analysenmethode?, GIT Labor-Fachzeitschrift 11 (2006) 996-997
2005
O. J. Schmitz, Analyse komplexer Mischungen, Nachrichten aus der Chemie 11 (2005) 1148-1151
2004
O. J. Schmitz in: P. Hering (Editor), Laser-induced analytical methods in environmental and health research:
DNA adducts as biomarkers for carcinogenesis analysed by capillary electrophoresis and laser-induced-fluorescence detection
Springer-Verlag Berlin, Heidelberg, New York (2004), Chapter 17, Pages 325-337
2001
O. J. Schmitz in: J. Cazes (Editor), Encyclopedia of Chromatography:
Carbohydrates: Analysis by Capillary Electrophoresis
Marcel Dekker, Inc. (2001), Chapter 45, Pages 133-135
Patents
2017
O. J. Schmitz, V. Wulf, L. Hyzak, M. Wirtz, D. Melchior, H.-W. Kling, S. Gäb, U. Gäb (legal representative)
US Patent 9,646,812
MALDI Sample Preparation Methods and Targets
2011
L. Hyzak, R. Moos, F. von Rath, V. Wulf, M. Wirtz, D. Melchior, H.-W. Kling, S. Gäb, O. J. Schmitz
EU application number 12753190.3 - 1803
MALDI Sample Preparation Methods and Targets
2005
T. Benter, K.-J. Brockmann, M. Constapel, S. Gäb, R. Giese, O.J. Schmitz
PCT/EP2005/005578 and DE 10 2004 025 841 B4
Verfahren und Vorrichtung zur massenspektroskopischen Untersuchung von Analyten
2000
M. Wießler, O. J. Schmitz, C. C. T. Wörth
Deutsche Patentanmeldung DE 100 02 402 A1
Verfahren zum Bestimmen von Nukleinsäure-Modifikationen
1998
O. Schmitz, D. Melchior, W. Schuhmann, S.Gäb
Deutsches Patent Nr. 19803264
Verfahren zur Herstellung von totvolumenfrei gekoppelten Kapillarsäulen in der Kapillarelektrophorese
Lectures
2023
Why GC-EI-MS when you can do better?
54th Annual Conference on the DGMS 2023, Dortmund, Germany, May 2023
How to solve problems in non-targeted analysis
analytiva Vietnam, Ho Chi Minh City, Vietnam, April 2023
2022
APCI, APPI, APLI, and DBD: Uncommon ionization methods for GC-MS
APCE-CECE-ITP-IUPAC Meeting 2022, Ankor Wat, Cambodia, November 2022
2D-LC: Hype or huge Potential?
Micro-, Nano and 2D-LC-Symposium: User meeting for miniaturized and multidimensional chromatography, Frankfurt, Germany, September 2022
Why use GC-EI-MS when you can do better?
International Symposium on Chromatography (ISC), Budapest, Hungary, September 2022
Why use GC-EI-MS when you can do better?
University of Rostock, Rostock, Germany, June 2022
2021
APCI, APPI, APLI, and DBD: Uncommon ionisation methods for GC- MS
QuoVadis LifeSciences, Opole, Poland, June 2021 (digital)
APCI, APPI, APLI and DBD as powerful ionization methods for GC-MS
Gas Chromatography meets Non-Target Screening, February 2020 (digital)
2020
Reduction of the elution power of the transfer solution to optimize a 2D-LC
Praxistag HPLC, May 2020 (digital)
Analysis of complex samples with LCxLC, LC-IMS or µLC+LC-IMS coupled to qTOF-MS: Who is the winner?
Analytica Munich conference, October 2020 (digital)
To the limits of feasibility: 2D-LC-ACD-HRdm-IM-qTOF-MS
Selectscience virtual analytical summit 2020, March 2020
The power of IM-MS and the benefit of multiplexing
6th International Ion-Mobility Spectroscopy Meeting, Essen, Germany, February 2020
2019
Chinese Herbs Analysis: The Power of Chromatography in Combination with Ion Mobility-Mass Spectrometry
3rd International Symposium on Advances in Pharmaceutical Analysis (APA), Xi´an, China, October 2019
Mass spectrometry: What needs to be improved?
Tsinghua University, Peking, China, October 2019
Challenges in single-cell analysis with mass spectrometry
18th International Beijing Conference and Exhibition on Instrumental Analysis (BCEIA), Beijing, China, October 2019
Use of SFC-IM-qTOF-MS for the analysis of sugars and lipids
Agilent LC/MS Seminar, Düsseldorf, Germany, October 2019
The power of chromatography in combination with ion mobility-mass spectrometry
25th International Symposium on Separation Science, Lódz, Poland, September 2019
The power of chromatography in combination with ion mobility-mass spectrometry
6th analytica Vietnam conference, Ho Chi Minh City, Vietnam, April 2019
How using an at-column dilution (ACD) Mmodulator can improve 2D-LC Analysis
Anakon 2019, Münster, Germany, March 2019
2D-LC-IM-qTOF-MS as a generic analytical method for the analysis of complex samples
5th International Ion Mobility Spectrometry (IMS) Meeting, Bordeaux, France, March 2019
From 1D-LC with 1000-mm columns to LC+LC-IM-qTOF-MS
Agilent's Innovative Separation Strategies for Enhanced MS Analysis European tour, Duesseldorf, Germany, February 2019
Ionenmobilitäts-Massenspektrometrie als leistungsstarkes Tool für die target, suspected target und non-target Umweltanalytik
36th Forum Analytik 2019, Vienna, Austria, February 2019
2018
µLC+LC-IM-qTOF-MS for complex samples such as lipidome or proteome
Analytica China conference, Shanghai, China, October 2018
Five-dimensional analysis (LC+LC-IM-qTOF-MS) for complex samples such as metablome, lipidome or proteome
International Symposium on Metabolic diseases and translational medicine, Dalian, China, October 2018
LC+LC- and GC+GC-IMS-qTOF-MS as a generic analytical platform and first results with a new GC-APCI ion source
Tsinghua University, Beijing, China, October 2018
Thousands of separated signals in a four-dimensional separation approach: How can we manage the data
SECyTA 2018, 18th meeting of the Spanish Society of Chromatography and Related Techniques,
Granada, Spain, October 2018
From one- to five-dimensional analysis platform: pros and cons
2nd 2D-LC / GC Symposium: User meeting for multidimensional chromatography
Frankfurt, Germany, September 2018
Multidimensional Chromatography coupled with Ion-Mobility Mass Spectrometry: Enough is enough
Analytica conference, Munich, Germany, April 2018
LC+LC- and GC+GC-IMS-qTOF-MS as a generic analytical platform and first results with a new GC-APCI ion source
Tsinghua University, Beijing, China, March 2018
LC+LC- and GC+GC-IMS-qTOF-MS in combination with a CCS data base as a generic analytical platform
University of Graz, Graz, Austria, March 2018
Einsatz der Ionenmobilitäts-Massenspektrometrie für suspected und non-target Fragestellungen: Ein kritischer Überblick
IUTA, Duisburg, Germany, March 2018
LC+LC- and GC+GC-IMS-qTOF-MS as a generic analytical platform
Dow-Chemicals, Stade, Germany, January 2018
Multidimensional Chromatography coupled with Ion Mobility - Mass Spectrometry: Hype or Ripe?
4th International Ion Mobility Spectrometry (IMS) Meeting, Uetrecht, The Netherlands, January 2018
2015 - 2017
Multidimensional Chromatography coupled with Ion Mobility - Mass Spectrometry: Hype or Ripe?
BCEIA, Beijing, China, October 2017
LC+LC- and GC+GC-IM-qTOF-MS as a potential tool in non-target analysis
HPLC, Prague, Czech Republic, June 2017
Novel trends in mass spectrometry
Hitachi, Ibaraki, Japan, May 2017
2D-LC and 2D-GC coupled with IMS-qTOF-MS as a potential tool for the analysis of Traditional Chinese Herbs
International Congress on Analytical Sciences (ICAS), Hainan, China, May 2017
A four-dimensional separation method for the comprehensive analysis of natural products
ANAKON, Tübingen, Germany, April 2017
2D-Chromatography coupled to IM-qTOF-MS for the analysis of complex samples such as medicinal plants
5th analytica conference, Hanoi, Vietnam, March 2017
New and unusual ionization methods for mass spectrometric analysis of nonpolar substances
Merck KGaA, Darmstadt, Germany, March 2017
A novel multi-dimensional separation approach for Lipidomics
10th analytica Anacon conference in Hyderabad, India, October 2016
LC+LC- and GC+GC-IM-qTOF-MS as a potential tool in non-target analysis
8th Shanghai International Symposium on analytical Chemistry in Shanghai, China, October 2016
Ion mobility spectroscopy as a powerful separation dimension in LC-MS
18th International Symposium on Advances in Extraction Technologies & 22nd International Symposium on Separation Sciences, Torun, Poland, July 2016
GC-IM-QTOF-MS – A new hyphenated separation technique for the analysis of complex samples
40th International Symposium on Capillary Chromatography and 13th GCxGC Symposium, Riva del Garda, Italy, June 2016
The four separation dimensions of 2D-LC-IM-qTOF-MS as an optimal tool for non-target analysis
Agilent Lunch seminar at 40th International Symposium on Capillary Chromatography and 13th GCxGC Symposium, Riva del Garda, Italy, June 2016
Ion Mobility Spectrometry as a Powerful Separation Dimension in LC-MS
Analytica conference, Munich, Germany, May 2016
Ion Mobility Spectrometry as a Powerful Separation Dimension in LC-MS
Agilent 6560 Ion Mobility Q-TOF LC/MS Workshop, Beijing, China, April 2016
Ion Mobility Spectrometry as a Powerful Separation Dimension in LC-MS
Agilent 6560 Ion Mobility Q-TOF LC/MS Workshop, Shanghai, China, April 2016
Panel discussion with Christian Minz (Eurofins) and Dr. Alexander Schiffer (Sanofi-Aventis)
Agilent meeting "Win as one", Berlin, Germany, March 2016
The four separation dimensions of 2D-LC-IM-qTOF-MS as an optimal tool for non-target analysis
DPhG-lecture at University of Freiburg, Freiburg, Germany, February 2016
2D-LC-IM-MS as the ultimate tool in non-targeted analysis
2nd European IM-MS User Meeting, Waldbronn, Germany, January 2016
A forgotten two-dimensional liquid chromatography approach coupled to an ion mobility-mass spectrometer
39th DICP Symposium on Functional metabolomics, Dalian, China, November 2015
Ion mobility spectroscopy as a new separation dimension in LC-MS
Metablomics IMS-QTOF Meeting, Duesseldorf, Germany, October 2015
Ion mobility spectroscopy as a new separation dimension in LC-MS (Tutorial)
9th analytica Anacon Conference, Hyderabad, India, October 2015
Personalized Medicine – or Metabolomics 2.0
Beijing-Humboldt Forum, Beijing, China, September 2015
New atmospheric pressure ion sources for mass spectrometry
Tsinghua University, Beijing, China, September 2015
2D-LC in combination with IMS and qTOF-MS for next generation metabolome analysis
Institute of Chemistry – Chinese Academy of Science (ICCAS), Beijing, China, September 2015
2D-LC in combination with IMS and qTOF-MS for next generation metabolome analysis
Peking University, Beijing, China, September 2015
Combination of the best of two worlds: LCxLC and IMS-QTOF-MS
Agilent Lunchseminar at 42nd HPLC Conference, Geneva, Switzerland, June 2015
Combination of the best of two worlds: LCxLC and IMS-QTOF-MS
Agilent Ion Mobility Workshop at Swedish Metabolomics Center, Umea, Sweden, May 2015
Combination of the best of two worlds: LCxLC and IMS-QTOF-MS
4th analytica Anacon Conference in Ho Chi Minh City, Vietnam, April 2015
Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook (part 1) Comprehensive two-dimensional liquid chromatography: Potential and Limitation (part 2)
Hanoi University of Science, Hanoi, Vietnam, April 2015
Comprehensive two-dimensional liquid chromatography: Theory and applications
2D-LC Symposium from Phenomenex, Frankfurt, Germany, March 2015
Combination of the best of two worlds: LCxLC and IMS-QTOF-MS
Pittcon 2015, New Orleans, USA, March 2015
Combination of the best of two worlds: LCxLC and IMS-QTOF-MS
Agilent Lunchseminar at 48th Annual Conference of the German Mass Spectrometry Society (DGMS) 2015, Wuppertal, Germany, March 2015
Combination of the best of two worlds: LCxLC and MS-QTOF-MS
Agilent Infinity II Tour, Frankfurt, Germany, January 2015
2012 - 2014
8th Analytical Anacon Conference in Hyderabad, India, November 2014 Possible Quality control of modern and folk medicine
The 7th Shanghai International Symposium on Analytical Chemistry, September 2014, Shanghai A novel ultra-sensitive GC-ion source for an Orbitrap-MS
30th International Symposium on Chromatography, September 2014, Salzburg, Austria Tutorial: Photo- and chemical ionization in atmospheric pressure mass spectrometry
8th International Cnference on Breath Research & CncerDiagnosis, July 2014, Torun, Poland Comprehensive two-dimensional Chromatography (GCxGC and LCxLC) for metabolom analysis
Fesenius Lecture of the GDCh, University of Bremen, January 2014 Product control of Chinese herbal medicine by comprehensive two-dimensional chromatography and novel ion sources
Fesenius Lecture of the GDCh, University of Muenster, December 2013 Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook
Fesenius Lecture of the GDCh, Applied University of Aalen, December 2013 Comprehensive two-dimensional liquid chromatography: potential and limitations
7th analytica Anacon India, November 2013, Mumbai, India How to find active agents in traditional folk medicine (Chinese Herbal Medicine)
35th DICP Symposium on New Separation/Analytical Methods and Metabolomics, October 2013, Dalian, China Using of shift gradient in second dimension to improve the separation space in LCxLC
15th BCEIA 2013, October 2013, Peking, China LCxLC with mixed-mode phases in the first dimension
IUTA, Duisburg, October 2013 Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook
ISAS, Dortmund, Sommer school, October 2013 Comprehensive two-dimensional liquid chromatography: potential and limitations
Fesenius Lecture of the GDCh, University of Rostock, July 2013 Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook
HPLC 2013, June 2013, Amsterdam, LCxLC analysis of Chinese Herbal Medicine
Fesenius Lecture of the GDCh, University of Gießen, June 2013 Comprehensive two-dimensional liquid chromatography: potential and limitations
Fesenius Lecture of the GDCh, University of Marburg, May 2013 Comprehensive two-dimensional liquid chromatography: potential and limitations
Analytica Vietnam, April 2013, Ho Chi Minh City, Quality control of Chinese Herbal Medicine with Comprehensive Two-Dimensional Chromatography and DIP-APCI-MS
Inaugural Lecture at the University of Duisburg-Essen, April 2013 Product control in traditional Chinese medicine: necessary and feasible?
Gerhard-Hesse-Prize Lecture, Anakon 2013, March 2013, Essen, Comprhensive two-dimensional liquid chromatography: potential and limitations
Agilent-User meeting, December 2012, Berlin DIP-APCI: A new tool for product analysis
Analytica China, October 2012, Shanghai Quality control of Chinese Herbal Medicine with comprehensive two-dimensional chromatography and DIP-APCI-MS
Sino-German Satellite symposium, October 2012, Shanghai DIP-APCI: A new ion source
Sino-German workshop, October 2012, Dalian Quality control of Chinese Herbal Medicine
Novia: User forum gas chromatography, May 2012, Bad Soden Theory, benefits, limitations and potential of GCxGC
Johannes Gutenberg-University, May 2012, Mainz Comprehensive two-dimensional analytical methods and new ionization techniques
Analytica Conference, April 2012, Munich Analysis of Chinese Herbal Medicine (CHM) with Comprehensive Two-Dimensional Chromatography
SIM-Seminar, March 2012, Oberhausen Development and optimization of a DIP-APCI-ion source
SUPELCO Seminar gas chromatography, März 2012, Hamburg The use of ionic liquid GC-columns in GCxGC-MS
SUPELCO Seminar gas chromatography, Februar 2012, Berlin The use of ionic liquid GC-columns in GCxGC-MS
2009 - 2011
Technical University of Munich, November 2011 Atmospheric-pressure laser ionization (APLI) in trace analysis: scientific findings, latest developments and outlook
14th Beijing Conference and Exhibition on Instrumental Analysis, Peking, October 2011 Quantitative MALDI-(TOF)MS analysis of synthetic polymers and peptides
HPLC 2011, Dalian, October 2011 A simple method for the determination of peak capacity in comprehensive two-dimensional liquid chromatography
Analytical forum BASF, Ludwigshafen, October 2011 Analysis of organic compounds in complex matrices with comprehensive separation techniques and modified ion sources
Annual meeting of the Association pour la recherché sur les nicotianees (ARN), Paris, March 2011 Analysis of DNA adducts: Development of a high-performance analytical platform to meet the challenges in human health
University of Duisburg-Essen, Essen, March 2011 Mass spectrometrical determination of biomarkers in complex matrices
Doktorandenseminar, Hohenroda, January 2011 What is the research group of Prof. Schmitz doing in Wuppertal?
CE-Forum at the Research Center Jülich, October 2010 Epigenetic determinations of cloned calfs and twins with MEKC-LIF
BIT's 1st Annual Tetra-Congress of MolMed-2010, Shanghai, October 2010 (Chair of Session Metabolomics and Metabonomics Approaches in Biomarker Discovery) Analysis of traditional chinese medicine with comprehensive separation techniques (LCxLC and GCxGC)
Sino-German-Symposia at Analytica China, Shanghai, September 2010 Analysis of traditional chinese medicine with comprehensive separation techniques (LCxLC and GCxGC)
Closing workshop of the Sino-German Cooperation Research Group for Separation and Analysis of Complex Samples, Dalian, January 2010 Analysis of Radix Angelicea sinensis with chiral GCxGC-qMS and the influence of aristolochic acid on the methylation level in rats
Shimadzu-Workshop, Duisburg, October 2009 Theory of multi-dimensional separation techniques
BGFA -Forschungsinstitut für Arbeitsmedizin der Deutschen Gesetzlichen Unfallversicherung, Bochum, September 2009
Research Topics in the Department of Analytical Chemistry at the University of Wuppertal
Workshop of the Sino-German Cooperation Research Group for Separation and Analysis of Complex Samples, Karlsruhe, July 2009 Analysis of TCMs and identification of new biological active drugs
University of Saarland, May 2009 A universal ionisation label for the APLI-(TOF)MS analysis of small molecules and polymers
ANAKON 2009, Berlin, March 2009 A universal ionisation label for the APLI-(TOF)MS analysis of small molecules and polymers
2005 - 2008
19th DICP Symposium on Frontier of Bioanalytical Techniques: Challenge of Metabolomics and other -omics, Dalian, November 2008 A universal ionisation label for the APLI-(TOF)MS analysis of small molecules and polymers
Hygiene-Institute Gelsenkirchen, September 2008 Atmospheric-Pressure Laser Ionization (APLI): A novel ionization method for the ultra-sensitive determination of aromatic compounds
University of Wuppertal, June 2008 Use of APLI-MS and CE-LIF for processing actual analytical questions
BIOSPEC Colloquium at the Research Center Jülich, May 2008 Atmospheric-Pressure Laser Ionization (APLI): A novel ionization method for the ultra-sensitive determination of aromatic compounds
University of Saarland, May 2008 Novel methods for ultra-trace analyses: APLI-MS and CE-LIF
Institute of Analytical Chemistry at the University of Regensburg, November 2007 Novel methods for ultra-trace analyses: APLI-MS and CE-LIF
37th Annual meeting of the European Environmental Mutagen Society, Basel, September 2007 Determination of the genome-wide DNA-methylation level with capillary electrophoresis
Institute of Inorganic and Analytical Chemistry, University Münster, June 2007 Determination of epigenetic changes (DNA-methylation level) at chemical carcinogenesis by CE-LIF
30th International Symposium on Capillary Chromatography, Dalian, June 2007 Ultra-sensitive determination of polycyclic aromatic compounds with atmospheric-pressure laser ionization (APLI) as an interface for GC-MS
Faculty of Science, Hong Kong Baptist University, June 2007 Ultra-sensitive determination of polycyclic aromatic compounds with atmospheric-pressure laser ionization (APLI) as an interface for LC and GC-MS
LC-MS Workshop at the annual meeting of the German Society on Mass Spectroscopy, Bremen, March 2007 Atmospheric-Pressure Laser Ionization (APLI) - A novel ionization method for coupling LC and GC with mass spectroscopy
Chemiedozententagung in Halle, March 2007 Determination of epigenetic changes (DNA-methylation level) at chemical carcinogenesis by CE-LIF
Department of Animal Science, University of Adelaide, December 2006 Determination of the DNA-methylation level with CE-LIF
Institute of Instrumental Analysis at the University of Universität Duisburg-Essen, November 2006 Atmospheric-Pressure
Laserionization (APLI): A novel ionization method for trace analysis of lipophilic aromatic compounds
Workshop on Biomarker of Exposure and Cancer Risk: DNA Damage and DNA Adduct Detection & 6th GUM-32P-Postlabelling
Workshop, Heidelberg, September 2006 (Chair of Session "VII") Determination of the DNA methylation level with capillary
electrophoresis and laser-induced fluorescence detection (CE-LIF)
Bayer CropScience, Monheim, September 2006 Atmospheric-Pressure Laserionization (APLI): A novel ionization method for trace analysis of lipophilic aromatic compounds
Bayer HealthCare AG, Wuppertal, April 2006 Analysis and molecular cancer epidemiology
Institute of Analytical Chemistry at the Philipps-Universität Marburg, April 2006 Novel methods for ultra-trace analysis: APLI-MS, GCxGC, CE-LIF
GSF - National Research Center for Environment and Health Institute for Ecological Chemistry, February 2006 Atmospheric-Pressure Laser Ionization (APLI): Mass spectrometric methods for the determination of aromatic hydrocarbons
Institute of Pharmaceutical and Medical Chemistry, University of Münster, October 2005 Determination of the DNA-Methylation level by Capillary Electrophoresis
11th Beijing Conference and Exhibition on Instrumental Analysis, Peking, October 2005 Atmospheric-Pressure Laser-Ionization (APLI) Mass Spectrometry for Determination of Aromatic Hydrocarbons
GDCh-Annual Meeting, Düsseldorf, September 2005 Panel discussion: Bachelor/Master = A successful structure for the following generation of chemists?
ANAKON 2005, Regensburg, March 2005 Atmospheric-Pressure Laser Ionization: A novel ionization method for LC-MS
Chemiedozententagung in Munich, March 2005 Analysis of endogenous DNA-damages in mitochondrial and genomic DNA by ultra-sensitive fluorescence spectroscopy
Biomarkers of Harm, Tobacco Toxicity, and Emerging Cancer Patterns and Etiology, St. Louis, February 2005 CE-LIF analysis of endogenous damage in mitochondrial and genomic DNA
2000 - 2004
7th Sino-German Symposium on Chromatography, Chongqing, October 2004 Comprehensive Two-Dimensional Gas Chromatography of Polycyclic Aromatic Hydrocarbons in Olive Oil
Center of Pharmacy at the University of Groningen, May 2004 DNA adduct analysis and determination of the methylation level with capillary electrophoresis and LIF
German Cancer Research Center Heidelberg (DKFZ), MArch 2004 Determination of carcinogens in complex matrices by comprehensive two-dimensional gas chromatography
5th National Postlabeling-Workshop, Berlin, April 2003 (Chair of session "Application areas") Analysis of DNA-adducts, apurinic sites and 5-methylcytosines by CE-LIF
16th International Symposium on Microscale Separations and Analysis (HPCE), San Diego, January 2003 CE-LIF - A useful tool for the investigation of molecular and metabolic mechanisms of cancerogenesis
Walther-Straub-Institute of Pharmacology and Toxicology at the Ludwig-Maximilians-University of Munich, December 2002
Determination of the Methylation level in tumor cells by capillary electrophoresis and laser-induced fluorescence detection
Working committee "Analysis of biological materiall" of the "Arbeitsstoffkommission (DFG)" in Bonn, November 2002
Determination of DNA-adducts as biomarkers of chemical carcinogenesis by capillary electrophoresis
Institute of Human Diet and Science of Nutrition at the Christian-Albrechts-Universität of Kiel, June 2002 Methods for the determination of biomarkers of chemical carcinogenesis and oxidative stress
Chemiedozententagung in Cologne, March 2002 Determination of DNA-adducts as biomarkers of chemical carcinogenesis by capillary electrophoresis
Pharmaceutical Faculty at the Ruprecht-Karls-University of Heidelberg, July 2001 Development of an analytical method for the determination of DNA-adducts by capillary electrophoresis
Institute for laser physics at the University of Bielefeld, March 2001 Determination of DNA-adducts as biomarkers of chemical carcinogenesis by CE-LIF
November AG, Erlangen, November 2000 Use of capillary electrophoresis in modern analysis
Schering AG, Berlin, October 2000 ▪ Capillary electrophoresis in modern analysis ▪ Development of an automatic genotoxicity test by analysis of fluorescence-labelled DNA-adducts
Fresenius HemoCare, Munich, September 2000 Analysis of poly clonal antibodies by fluorescent labelling and cIEF with multi-laser-induced fluorescence detection
Institute for Biological Research (INBIFO GmbH), Cologne, August 2000 Development of an automatic genotoxicity test by analysis of fluorescent labeled DNA-adducts
3th Asia-Pacific International Symposium on Capillary Electrophoresis and Related Microscale Techniques (APCE), Hong Kong, June 2000 Analysis of Fluorescent labeled DNA-Adducts by Micellar Electrokinetic Chromatography
13th International Symposium on High Performance Capillary Electrophoresis & Related Microscale Techniques (HPCE), Saarbrücken, February 2000 Analysis of Fluorescent labeled DNA-Adducts by Micellar Electrokinetic Chromatography
1995 - 1999
International Workshop of Food Preparation Methods and Cancer Risk, Heidelberg, November 1999 Development of a fluorescence-based method to determine DNA-adducts by capillary electrophoresis
4th National Postlabeling-Workshop, Wuppertal, October 1999 Postlabeling and Capillary Electrophoresis
Analytica Conference 98, München, April 1998 Analyse von Lipidhydroperoxiden mit HPLC und CE